Yersinia pestis

The experimental plague-vector efficiency of wild rodent fleas compared with Yersinia pestis cheopis, together with observations on the influence of temperature.

Disappearance of the disease is unlikely due to the wide range of mammalian hosts and their attendant fleas. We co-cultured bacteria for durations of 10 min, 30 min, and 24 h to assess proximal and delayed effects of phagocytosis on bacterial cell viability and intraameba bacterial location.

Hospital staff will take special steps to prevent the spread of the plague bacteria to other people. These factors are important for adhesion and injection of proteins into the host cell, invasion of the bacteria and binding of iron from red blood cells. It can also happen if the Y.

Regulation and polarized transfer of the Yersinia outer proteins Yops involved in antiphagocytosis. Yersinia pestis--etiologic agent of plague. Ben-Gurion R, Shafferman A. The ail locus is found uniquely in Yersinia enterocolitica serotypes commonly associated with disease.

Finally, these proteins also target NK cells, which further inhibit the innate immune response. Steps in Pathogenesis Most mammals can be infected.

YopT is a cysteine protease that inhibits RhoA by removing the isoprenyl groupwhich is important for localizing the protein to the cell membrane. Immunochemical analysis of plasmid-encoded proteins released by enteropathogenic Yersinia sp. Chaperones assist with transportation of the effectors and translocators, and regulatory components regulate the system [16].

Occasionally, other species become infected, causing an outbreak among animals, called an epizootic.

Uninfected ameba control lysates consistently yielded zero bacteria across all ameba species and treatments data not shown. Through these carriers, Yersinia pestis is able to invade human cells and create diseases.

Genome[ edit ] The complete genomic sequence is available for two of the three subspecies of Y.

Yersinia pestis

Intracellular replication of Y. Through the action of this PLD, Y. OVERVIEW. Plague or black death is an infection of rodents caused by Yersinia pestis and accidentially transmitted to humans by the bite of infected fleas.

The disease follows urban and sylvatic cycles and is manifested in bubonic and pneumonic forms [note: bubo is derived from a Greek word for groin]. Classification Higher order taxa. Kingdom: Yersinia pestis Phylum: Proteobacteria Class: Gamma Proteobacteria Order: Enterobacteriale Genus: Yersinia Species.

Yersinia pestis. Description and significance. Yersinia pestis was discovered in Hong Kong in by a Swiss physician Alexandre Yersin, who was a student of the Pasteur school of thought.

He linked Y. pestis to the bubonic. General characteristics. Y. pestis is a nonmotile, stick-shaped, facultative anaerobic bacterium with bipolar staining (giving it a safety pin appearance) that produces an antiphagocytic slime layer. Similar to other Yersinia species, it tests negative for urease, lactose fermentation, and indole.

The closest relative is the gastrointestinal pathogen Yersinia pseudotuberculosis, and more. Yersinia pestis: The bacteria that causes the bubonic plague which in the year (as the Black Death) and later in the Middle Ages decimated Europe.

The effects of the plague are described in the nursery rhyme "We all fall down." Y. pestis mainly infects rats and other rodents which are the.

Yersinia Pestis (Pathogenesis)

Plague ecology in the United States. A downloadable version [PDF – 1 page] is also available. The bacteria that cause plague, Yersinia pestis, maintain their existence in a cycle involving rodents and their fleas.

In urban areas or places with dense rat infestations, the plague bacteria can cycle. Description.

Yersinia Pestis (Pathogenesis)

Yersinia pestis is a zoonotic pathogen that is most commonly transmitted through fleas that feed on infected rodents.Y.

pestis is a Gram-negative, non-motile, non-spore-forming coccobacillus that is also a facultative anaerobe.

Ecology and Transmission

In the past, this pathogen ravaged cities throughout Europe, Asia, and Africa, takin thousands of lives with sudden outbreaks.

Yersinia pestis
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Yersinia Pestis (Pathogenesis) - microbewiki